Abstract: High speed serial bus is compatible in the architecture of VPX bus specification．VPX bus has extensive application prospect in high-performance embedded computing area．The 3U and 6U module and backboard of chassis are described and analyzed，and a project of embedded system base on VPX bus is also shown in this paper．The module is designed with PowerPC MPC8641D and RapidIO switch Tsi577．The backboard is designed with mesh topology architecture，which supports high speed point to point communication．The powerful ability of data processing and data exchange is a trend of military information processing system of radar．