Abstract: The resistance module has large power and too concentrated heat consumption. The design of the cooling system for the module is both important and difficult. The quality of the cooling system is directly related to the work of the module. The module with both great thermal density and large power is discussed in this paper. The forced liquid cooling is chosen as its cooling method. Then constant optimization for the design of the cold plate is carried out by simulation. By adding heat dissipation teeth and modifying their structures, the heat dissipation demands of the cold plate are satisfied. ANSYS is used to simulate the sealing performance of the cold plate with different structures and forms. By adopting stainlesssteel cover plate with stiffeners, good sealing performance is obtained and the manufacturing cycle and cost of the cold plate are reduced. After installation, the prototype test of the cold plate indicates its feasibility.